Every fold in the curated distillation set (7,757) is a redundancy-reduced cluster
representative that is novel vs the v341 PDB training set. All filtering happens live in your browser;
settings persist across reloads.
Identity & size
Search
Matches the seq_id, the human-readable name, or the sublibrary.
Length
Design-region length in nucleotides (excludes the fixed primer/barcode padding).
Model confidence, 0–100; higher = more confident. The pool bar is pLDDT>85.
clashscore
Steric clashes per 1000 atoms (Phenix); lower = cleaner geometry. Populated on curated reps.
Novelty
best_tm1
USalign TM1 to the closest of the 2,243 v341 PDB-RNA chains. Lower = more novel (≲0.45 novel, ≲0.40 clearly novel). Fold-level for the whole set; the deck candidates use a per-structure value.
nearest
The closest known PDB chain found for that TM1; hover (or see the deep view) for the RCSB entry title — handy for sanity checks.
overlap_AE
For an F–H fold, the TM1 to its closest A–E fold — i.e. how structurally redundant it is across the natural/synthetic sets. Lower = more distinct.
Chemical mapping (SHAPE/DMS)
SHAPE
yes = the fold's tertiary-motif residues are protected (mean 2A3 protection > 0) or the fold's reactivity agrees with its predicted pairing (r(2A3) < −0.2). no = reactivity exists but doesn't indicate protection. n/d = no usable protection signal (no tertiary motif to score, or no reactivity coverage) — the raw reactivity may still be viewable in the fold's deep view. A–E reactivity is read from the experiment HDF5s; F–H from the full design-aligned chemmap.
SHAPE agr
SHAPE–pairing agreement: correlation of 2A3 reactivity with the unpaired positions. Positive = good (reactive where unpaired, protected where paired ⇒ the chemical mapping supports the predicted fold). This is the sign-flipped r(2A3,is-paired).
In a fold's deep view, the pairing track (white = paired, light red = unpaired) sits under the DMS/2A3 reactivity rows so you can visually check agreement: unpaired (light red) should line up with reactive (red) reactivity. Pairing comes from the fold representative's predicted secondary structure.
Structure
Compactness
C1′–C1′ contact ratio: number of nucleotide pairs whose C1′ atoms are within 8 Å (sequence separation ≥ 6), divided by length. A globularity proxy (the RNA analog of the AlphaFold-DB Cα contact ratio). Higher = more compact / globular; an extended chain scores near 0.
Base-paired fraction
Fraction of positions that are paired in the fold's predicted secondary structure (dot-bracket). Higher = more structured. Computed on the fold representative.
Motifs & topology
Motifs
Tertiary RNA motifs detected by Rosetta rna_motif (A-minor, TL-receptor, T-loop, U-turn, platform, …). Filter by "≥1 tertiary", "a rare tertiary", or specific types. tert/rare columns count them.
Pseudoknot
The predicted secondary structure contains crossed base pairs.
Ranking & display
Ranking · top-N · per letter
Sort key (novelty, compactness, base-paired fraction, pLDDT, length, …) and how many rows to show — overall, or top-N within each library. Click any column header to sort by it.
Base colors
Toggle the sequence-strip nucleotide palette (A gold · C green · G red · U blue).
Deep view (click any row)
3D structure
Interactive cartoon colored by 2A3 reactivity (blue = protected → red = reactive); tertiary-motif residues shown as colored sticks. Dock it centered / right / bottom via the header layout buttons.
Tracks
Motif lanes · sequence · DMS · 2A3 reactivity, aligned on the design-sequence position axis.